Epidural Steroid Injections NYC — Fluoroscopic-Guided Spinal Injections at New York Bone & Joint

Written by: Efime Popovitz, MD

Dual Board-Certified Anesthesiology & Pain Medicine (ABA) | Fellowship-Trained Pain Medicine, Yale School of Medicine | Interventional Pain Management | NY Bone & Joint Specialists

Date Published: June 4, 2026

Last Updated: June 29, 2026

Last Medically Reviewed: June 29, 2026

This page has been written and reviewed by a fellowship-trained, board-certified orthopedic surgeon with over 20 years of clinical experience. All clinical claims are supported by peer-reviewed literature and current AAOS and AOSSM guidelines. See References section below.

At a glance

  • What it is: A minimally invasive procedure in which corticosteroid medication is injected into the epidural space (the area surrounding the spinal cord’s protective covering) to reduce inflammation around compressed or irritated spinal nerve roots, relieving back pain and leg or arm pain from nerve compression.
  • What it treats: Lumbar radiculopathy (sciatica), cervical radiculopathy (pinched nerve), lumbar and cervical spinal stenosis, herniated disc with nerve root compression, degenerative disc disease with radicular symptoms, and post-surgical nerve root irritation.
  • Approaches available: Interlaminar ESI (broad epidural space delivery), transforaminal ESI / selective nerve root injection (targeted single nerve root), and caudal ESI (lower lumbar and sacral delivery). Cervical, thoracic, and lumbar levels all performed at NYBJ.
  • Who performs it: Dr. Efime Popovitz, dual board-certified in Anesthesiology and Pain Medicine, fellowship-trained at Yale School of Medicine. All injections performed at New York Bone & Joint Specialists, Upper East Side and Midtown Manhattan.
  • Guidance: Fluoroscopic (X-ray) guidance used as standard. Contrast dye confirms epidural space placement before corticosteroid is injected. This is not a landmark-guided procedure.
  • What to expect: In-office procedure, 20–30 minutes, same-day return home. Relief typically begins within 3–5 days and may last weeks to several months. Generally no more than 3 injections per 6-month period.
  • Insurance: Covered by most major insurance plans for documented indications. Coverage verified before scheduling.

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About this page

This page was written and is maintained by Efime Popovitz, MD, a dual board-certified pain management physician (Anesthesiology and Pain Medicine, American Board of Anesthesiology) fellowship-trained at Yale School of Medicine. Dr. Efime Popovitz practices at New York Bone & Joint Specialists, a private orthopedic and pain management practice with two Manhattan locations: Upper East Side and Midtown. Epidural steroid injections at New York Bone & Joint are performed under fluoroscopic guidance for lumbar, thoracic, and cervical indications, including sciatica, herniated disc, spinal stenosis, and cervical radiculopathy. New York Bone & Joint is independent of hospital systems and operates as a private practice serving patients across New York City and the surrounding region.

Introduction

An epidural steroid injection (ESI) is one of the most widely used and, when properly selected and precisely administered, most effective non-surgical treatments for back and leg pain caused by spinal nerve compression. The corticosteroid delivered into the epidural space reduces the inflammation that’s amplifying the pain signal from a compressed nerve root, providing meaningful relief that allows patients to complete physical therapy and, in many cases, avoid surgery altogether. [1] [2]

The critical variables are diagnosis, approach, and accuracy. The diagnosis determines whether an ESI is the right treatment. The approach (whether interlaminar, transforaminal, or caudal) determines where the medication is delivered. And the accuracy of needle placement, confirmed with fluoroscopic imaging and contrast dye, determines whether the medication reaches the intended target. At New York Bone & Joint, all three are addressed before the needle is placed.

Dr. Efime Popovitz performs epidural steroid injections under fluoroscopic guidance as the standard for all spinal procedures at New York Bone & Joint. His dual board certification in Anesthesiology and Pain Medicine and fellowship training at Yale School of Medicine provide the anatomical depth and procedural precision that ESI outcomes require. His evaluation of every patient begins with the two questions that should precede every injection: is this the right treatment for this specific patient, and can I place it where it will actually work?

What is an Epidural Steroid Injection and What Does It Do?

The epidural space is a narrow corridor running the length of the spine between the bony spinal canal and the dura, the protective covering of the spinal cord and nerve roots. When nerve roots are compressed by a herniated disc, narrowed by spinal stenosis, or inflamed by degenerative changes, they generate the pain, numbness, and weakness that patients experience in the back, legs, or arms.

An epidural steroid injection delivers corticosteroid medication directly into this epidural space, reducing the local inflammatory response around the affected nerve roots. The result is a reduction in the inflammation that’s amplifying the nerve’s pain signal, not a correction of the structural problem causing the compression. This is the most important distinction to understand before proceeding: an ESI treats the inflammatory component of nerve root pain. It doesn’t repair a herniated disc, widen a stenotic canal, or stabilize a degenerative spine. [2]

For many patients, that distinction matters less than it sounds. When a disc herniation compresses a nerve root, the inflammatory response around that nerve is often responsible for the majority of the pain. Reducing it can produce dramatic relief while the disc, which has lost its blood supply at the point of herniation, begins to resorb over weeks to months. An ESI that quiets the nerve for 8 to 12 weeks, combined with structured physical therapy, can be the intervention that allows the natural healing process to complete.

“Every patient I see before a spinal injection gets the same explanation: the injection addresses inflammation, not anatomy. If your pain is coming primarily from nerve root inflammation around a herniated disc, you may get significant relief. If it’s coming primarily from mechanical instability, severe canal narrowing that leaves no room for the nerve regardless of inflammation, or a structural problem that requires surgical correction? The injection will tell us that, too. A diagnostic ESI that provides only partial or brief relief is still valuable clinical information. It tells us where the problem isn’t, which helps us find where it is.” — Dr. Efime Popovitz

The Three Approaches: Interlaminar, Transforaminal, and Caudal

Epidural steroid injections are not a single technique. Three distinct approaches are used at New York Bone & Joint, each with different anatomical targets, indications, and advantages. The choice of approach is based on the patient’s diagnosis, the level of pathology, the symptoms’ distribution, and what the imaging shows.

ApproachNeedle PlacementMedication DeliveryBest Indicated ForKey Advantage
Interlaminar ESIBetween the laminae of adjacent vertebrae, into the posterior epidural spaceBroad delivery to the epidural space at the targeted level and adjacent levelsBilateral symptoms, multi-level involvement, diffuse nerve root irritationCovers a broader area; useful when the specific level is uncertain or when bilateral symptoms need treatment
Transforaminal ESI (Selective Nerve Root Injection)Adjacent to the specific nerve root as it exits through the foramen at the affected levelHighly targeted delivery directly to the nerve root sleeve at the foraminal openingSingle-level, unilateral radiculopathy with clear imaging correlation (e.g., L5-S1 disc herniation causing left L5 radiculopathy)Most targeted approach; highest drug concentration at the specific nerve root; also functions as a diagnostic injection confirming the symptomatic level [7]
Caudal ESIThrough the sacral hiatus at the base of the spineDelivery to the lower lumbar and sacral epidural spaceLower lumbar and sacral nerve root symptoms; post-surgical epidural fibrosis at lower lumbar levelsAvoids the lumbar epidural space directly; useful when post-surgical scarring or anatomy makes lumbar approaches technically difficult

“The choice between interlaminar and transforaminal is one of the most consequential decisions in spinal injection practice. Transforaminal delivery places the medication directly at the site of nerve root compression. It’s the most targeted approach and, for single-level unilateral radiculopathy with clear imaging correlation, typically produces the best outcomes. But it requires more precise needle placement and fluoroscopic confirmation. Interlaminar is more forgiving anatomically and covers more territory, but the medication distribution is less predictable. I choose based on the clinical picture, imaging, and patient’s symptom pattern rather than on what’s technically easier.” — Dr. Efime Popovitz

Conditions and Indications

Epidural steroid injections are indicated for specific conditions involving nerve root inflammation or compression along the spinal axis. The following are the primary indications treated at New York Bone & Joint: [1] [2]

ConditionMechanismESI ApproachExpected Benefit
Lumbar Radiculopathy (Sciatica)Disc herniation or foraminal stenosis compressing the lumbar nerve root, producing pain, numbness, or weakness radiating down the leg in a dermatomal patternTransforaminal ESI at the affected level (preferred) or interlaminar ESIStrong evidence for short-term leg pain reduction. [3] Most effective when combined with structured physical therapy. Best candidates: acute to subacute herniation, clear single-level imaging correlation.
Lumbar Spinal StenosisNarrowing of the spinal canal compressing multiple nerve roots, producing neurogenic claudication; leg pain and weakness with walking that improves with sitting or forward flexionLumbar interlaminar ESI or caudal ESIModerate evidence for functional improvement and pain reduction. [4] [5] Particularly useful for patients who cannot complete PT due to pain. May reduce need for surgical decompression in some patients.
Cervical RadiculopathyDisc herniation or foraminal stenosis in the cervical spine compressing a nerve root, producing arm pain, numbness, or weaknessCervical interlaminar ESI or cervical transforaminal ESI (at experienced centers only)Good evidence for short-term relief of arm pain and neurological symptoms. [2] Cervical transforaminal carries higher technical risk and requires specialist-level precision. [7]
Herniated Disc (Lumbar or Cervical)Disc material compressing a nerve root with associated perineural inflammationTransforaminal ESI at the herniated levelStrong evidence for radicular symptom relief. [2] [3] Allows physical therapy to proceed during the natural resorption process. Best outcomes when performed within 6–12 months of onset.
Degenerative Disc Disease with RadiculopathyHeight loss and disc degeneration producing foraminal narrowing and nerve root irritationInterlaminar or transforaminal ESI at affected levelsUseful for acute flares with radicular symptoms. Less effective for pure axial (back-only) pain without radiculopathy.
Post-Surgical RadiculopathyResidual nerve root inflammation after spine surgery; epidural fibrosis causing ongoing painCaudal ESI or transforaminal at the affected levelHelps differentiate recurrent disc herniation from scar tissue (epidural fibrosis). Can reduce post-surgical nerve root inflammation.
When ESI is not the right answer: Epidural steroid injections aren’t appropriate for axial back pain without a radicular component, patients with spinal instability or spondylolisthesis requiring surgical stabilization, patients with symptoms of spinal cord compression (myelopathy), or patients with active infection or bleeding disorders. At New York Bone & Joint, the evaluation preceding any ESI includes a screen for contraindications, and we will tell you directly if injection isn’t the right approach for your condition.

Why Fluoroscopic Guidance is Non-Negotiable at New York Bone & Joint

Landmark-guided spinal injections, placed using surface anatomy and palpation without imaging confirmation, produce less reliable outcomes than fluoroscopically guided injections. Studies consistently show that fluoroscopic guidance significantly improves needle placement accuracy and clinical outcomes compared to blind technique for most spinal targets. [6]

At New York Bone & Joint, fluoroscopic guidance is the standard for all epidural steroid injections. Here’s what it means for your procedure:

  • Real-time imaging: Fluoroscopy provides live X-ray imaging throughout the procedure, allowing precise needle advancement to the target with continuous visualization of the needle tip position.
  • Contrast confirmation: Before any medication is injected, contrast dye is introduced through the needle. The spread of contrast on fluoroscopy confirms that the needle is correctly positioned within the epidural space and that medication will reach the intended target. If the contrast doesn’t spread as expected, the needle is repositioned before injection.
  • Vascular safety: Contrast under live fluoroscopy reveals inadvertent vascular placement, a safety check that can’t be performed with a blind injection. Intravascular injection of corticosteroid carries rare but serious neurological risks. [8] Fluoroscopic confirmation eliminates this risk.
  • Documentation: Fluoroscopic images are part of the procedure record, providing a verifiable record of needle placement for every injection.

“Patients sometimes ask me whether the fluoroscopy is necessary or whether it adds to the procedure cost. My answer is the same every time: accurate placement is the single most important variable in whether your injection works. The fluoroscopy isn’t optional equipment. It’s how I know the medication is going where it needs to go.” — Dr. Efime Popovitz

From Dr. Efime Popovitz: Why Where You Place the Needle Is Everything

A 32-year-old financial analyst came to see me with left leg sciatica that had been present for several months following a sudden onset of low back pain after performing a deadlift exercise at the gym. He knew his anatomy well enough to describe it precisely: pain starting in the left buttock, shooting down the posterior thigh to the calf, with intermittent numbness in the lateral foot. Classic L5-S1 nerve root pattern.

He had initially received an interlaminar epidural steroid injection at L5-S1 with approximately 60-70% improvement of his symptoms that lasted only 3 weeks.

His MRI showed a large left paracentral L5-S1 disc herniation with significant compression of the left S1 nerve root at the axilla of the root sleeve. The prior injection, based on the interlaminar approach, was spreading medication broadly rather than delivering it to the compressed nerve root sleeve where it needed to go.

I performed a left L5-S1 transforaminal epidural steroid injection under fluoroscopic guidance, with contrast confirmation of needle position at the S1 nerve root sleeve before injection. Within 48 hours he had approximately 80% reduction in leg pain. He completed a structured lumbar physical therapy program over the following eight weeks. At three months, his sciatica had fully resolved.

What I want patients to understand is that an injection that fails isn’t evidence that injections don’t work for your condition. It’s evidence that the injection didn’t reach its target. The diagnosis was correct. The treatment was correct. The delivery was the variable and in this case a transforaminal epidural injection was the more ideal approach. 

— Dr. Efime Popovitz, MD

What to Expect: Before, During, and After

Before the Procedure

Dr. Efime Popovitz will review your symptoms, examine the relevant spinal levels, and confirm the appropriate indication and approach based on your imaging and clinical picture. If you don’t have recent MRI, we will arrange it before scheduling the injection. You will receive pre-procedure instructions including any medication adjustments (particularly blood thinners), fasting requirements if sedation is used, and transportation arrangements. Most patients don’t require sedation for an ESI, but it’s available for anxious or complex cases.

During the Procedure

The procedure takes 20–30 minutes. You’ll lie on the fluoroscopy table in a position that optimizes access to the target level. The skin is cleaned and a local anesthetic is injected to numb the entry point. The spinal needle is then advanced under fluoroscopic guidance. Contrast dye is injected to confirm epidural placement. The corticosteroid is then delivered. You may feel pressure during the procedure and, in some cases, transient reproduction of your symptoms as the needle approaches the nerve root. This is normal and brief.

After the Procedure

Most patients go home within 30 minutes of the procedure’s completion. You may experience a temporary increase in back or leg pain for 24–48 hours as the local anesthetic wears off before the steroid takes effect. Pain relief typically begins within 3–5 days. We recommend avoiding strenuous activity for 24 hours. Most patients return to desk work the same day or the next day.

Risks and Considerations

Epidural steroid injections have an excellent safety record when performed by an experienced physician under fluoroscopic guidance. The following risks should be understood: [2] [8]

  • Post-procedure soreness: Temporary pain at the injection site or brief increase in symptoms for 24–48 hours is common and resolves without intervention.
  • Steroid effects: Temporary blood glucose elevation (important for diabetic patients to monitor), transient facial flushing, and rarely, systemic steroid effects. Your physician will advise based on your medical profile.
  • Headache (dural puncture): If the needle inadvertently enters the dural space (a wet tap), a positional headache can result. This is uncommon with experienced practitioners and fluoroscopic guidance, and is managed conservatively or with a blood patch if persistent.
  • Infection: Rare with standard sterile technique. Less than 1 in 10,000 procedures.
  • Rare neurological complications: Epidural hematoma, abscess, or spinal cord injury are exceedingly rare but require immediate recognition and management. Fluoroscopic guidance and contrast confirmation significantly reduce the risk of inadvertent vascular injection. [8]
  • Incomplete or short-lived relief: Not every patient responds to every ESI. If two well-placed injections at the correct level don’t provide meaningful relief, the diagnosis should be re-evaluated. Continued injection without a treatment response is not a strategy.

At your consultation, Dr. Efime Popovitz will review the specific risks relevant to your procedure, medical history, and medications.

Why Choose New York Bone & Joint for Epidural Steroid Injections?

The New York Bone & Joint AdvantageWhat It Means for You
Fluoroscopic guidance as standard, not optionalEvery spinal injection at New York Bone & Joint uses fluoroscopic imaging and contrast confirmation. Accurate placement is the single most important determinant of outcome. [6]
Dual board-certified pain specialistDr. Efime Popovitz holds dual board certification in Anesthesiology and Pain Medicine through the American Board of Anesthesiology, with fellowship training specifically in pain medicine at Yale School of Medicine.
Three ESI approaches availableInterlaminar, transforaminal, and caudal. Approach is selected based on your specific diagnosis, level, and symptom pattern, not on what is easiest.
All spinal levels: cervical, thoracic, lumbarFull spine coverage. Cervical radiculopathy patients do not need a separate referral.
Diagnostic precisionA transforaminal ESI that provides significant relief confirms the symptomatic level. A response that is partial or absent is also clinical information that guides the next step.

References

  1. American Academy of Orthopaedic Surgeons. Epidural Steroid Injections. OrthoInfo. orthoinfo.aaos.org/en/treatment/spinal-injections
  2. Cohen SP et al. Epidural steroid injections: a comprehensive evidence-based review. Pain. 2013. pubmed.ncbi.nlm.nih.gov/23598728
  3. Abdi S et al. Epidural steroids in the management of chronic spinal pain: a systematic review. Pain Physician. 2007. pubmed.ncbi.nlm.nih.gov/17256030
  4. Manchikanti L et al. Epidural injections for lumbar radiculopathy and spinal stenosis. Pain Physician. 2015. pubmed.ncbi.nlm.nih.gov/27008296
  5. Soin A et al. Lumbar Epidural Steroid Injections for Chronic Spinal Pain: A Clinical Review of Efficacy and Evidence. Cureus. 2025. pubmed.ncbi.nlm.nih.gov/41487815
  6. Shen PC et al. Comparison of ultrasound- vs. landmark-guided injections for musculoskeletal pain: an umbrella review. J Rehabil Med. 2024. pubmed.ncbi.nlm.nih.gov/39185547
  7. Chang-Chien GC et al. Transforaminal versus interlaminar approaches to epidural steroid injections. Pain Physician. 2014. pubmed.ncbi.nlm.nih.gov/25054401
  8. Horlocker TT et al. Anticoagulation and neuraxial procedures: practice advisory. ASRA. 2018. asra.com/guidelines-articles
  9. Friedly JL et al. A randomized trial of epidural glucocorticoid injections for spinal stenosis. JAMA. 2014. pubmed.ncbi.nlm.nih.gov/24988555
  10. American Academy of Orthopaedic Surgeons. Herniated Disk in the Lower Back. OrthoInfo. orthoinfo.aaos.org/en/diseases–conditions/herniated-disk-in-the-lower-back

FAQs

An epidural steroid injection (ESI) is a minimally invasive procedure in which corticosteroid medication is delivered into the epidural space of the spine to reduce inflammation around compressed or irritated nerve roots, relieving back pain and radiating leg or arm pain. [1] The procedure is performed under fluoroscopic guidance with contrast confirmation of needle placement at New York Bone & Joint. It doesn’t repair structural spinal pathology but reduces the inflammatory component of nerve root pain, often allowing physical therapy to proceed and facilitating natural healing.


Most patients experience pain relief for weeks to several months following an epidural steroid injection, with studies showing average relief of 3 to 6 months for lumbar radiculopathy from disc herniation. [3] Duration varies by condition, injection approach, accuracy of placement, and whether the injection is combined with structured physical therapy. Relief that diminishes faster than expected is a signal to re-evaluate the treatment plan rather than simply repeat the injection.


An interlaminar ESI delivers medication broadly into the posterior epidural space, while a transforaminal ESI (also called a selective nerve root injection) targets a specific nerve root at the foramen where it exits the spinal canal. [7] Transforaminal delivery places the highest concentration of medication directly at the compressed nerve root and is preferred for single-level, unilateral radiculopathy with clear imaging correlation. Interlaminar delivery covers a broader area and is preferred for bilateral or multi-level symptoms. The choice of approach is based on your specific diagnosis and symptom pattern.


Generally no more than 3 epidural steroid injections in a 6-month period is the standard guideline, with the number informed by the clinical response and the underlying condition. [2] If the first injection provides significant relief that then fully returns, a second injection may be appropriate. If the first injection provides no meaningful relief, the diagnosis should be re-evaluated before proceeding to a second injection rather than repeating the same procedure. Repeated injections without a clinical response isn’t a treatment strategy.


No, an epidural steroid injection treats the inflammation around a herniated disc’s compressed nerve root, not the disc herniation itself. [2] [10] However, many disc herniations resorb naturally over weeks to months. The injection reduces the nerve root’s inflammatory response during that resorption period, which often allows the patient to complete physical therapy and function more normally while the disc heals. For patients whose disc herniations resorb and whose nerve root inflammation resolves, the outcome can be equivalent to surgery, without the surgery.


No, while both use the epidural space, an epidural for childbirth delivers local anesthetic to block all sensation from the lower body, while an epidural steroid injection for pain delivers a small volume of anti-inflammatory corticosteroid to a specific spinal level to reduce nerve root inflammation. The goals, medications, volumes, and techniques are entirely different. A pain management epidural steroid injection typically doesn’t cause numbness or affect your ability to walk.


If a well-placed epidural steroid injection at the correct level doesn’t provide meaningful relief, that result is clinically informative, suggests that inflammation alone isn’t the primary driver of your symptoms, and that a structural problem or alternative pain source should be re-evaluated. At New York Bone & Joint, a non-response is followed by a diagnostic conversation about what the result tells us and what the next step should be, which may include a different injection type, surgical evaluation, or further imaging. We don’t repeat procedures that aren’t working.


In most cases, yes, recent MRI is needed to confirm the structural diagnosis, identify the symptomatic level, and plan the injection approach. Without imaging, we can’t confirm that the nerve root compression seen on MRI correlates with the symptoms being treated, or that the injection is targeting the correct level. If you don’t have a recent MRI, we will arrange it before scheduling your injection. We prefer high-field MRI (1.5T or 3T) for spinal evaluation.


Epidural steroid injections are covered by most major insurance plans when medically indicated, with documented diagnosis, appropriate conservative treatment prior to injection, and imaging confirming structural pathology. Our team will verify your specific coverage before scheduling and provide a clear picture of any out-of-pocket responsibility in advance.


Medically Reviewed by Dr. Popovitz.

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