Introduction
Cortisone injections are one of the most commonly performed procedures in orthopedic medicine. When administered for the right condition, at the right time, with accurate placement, a cortisone injection can provide meaningful pain relief that allows a patient to complete physical therapy, return to activity, or avoid surgery altogether. When it is not the right answer, it relieves pain without addressing the cause, and in doing so can delay the correct diagnosis by weeks or months. [1]
At New York Bone & Joint Specialists, our sports medicine physicians and orthopedic surgeons administer cortisone injections as a precisely indicated component of a complete treatment plan, not as a first response to any joint pain. Every patient who comes to New York Bone & Joint Specialists for an injection first receives an evaluation that confirms the appropriate indication, reviews existing imaging, and establishes what the injection can realistically achieve. We use ultrasound guidance to maximize injection accuracy. And we set honest expectations about duration of relief, frequency limits, and what a diminishing response to repeated injections means for the underlying condition.
This page covers cortisone injections for all orthopedic conditions across all body regions from shoulder, knee, hip, and spine to foot and ankle with specific guidance on indications, what to expect, how often they can be repeated, and when cortisone is not the right answer.
How Cortisone Injections Work
Cortisone is a corticosteroid, a synthetic version of the anti-inflammatory hormone your body naturally produces. When injected directly into a joint, bursa, or soft tissue, it reduces the local inflammatory response: decreasing swelling, calming the immune reaction driving the inflammation, and in doing so, reducing pain. [1]
The critical distinction is what cortisone does and does not do. It treats inflammation. It doesn’t repair torn tendons, heal cartilage, fix structural instability, or resolve mechanical problems. When pain is caused primarily by inflammation (such as bursitis, synovitis, tendinitis, inflammatory arthritis), cortisone can be highly effective. When pain is caused by a structural problem (such as a torn rotator cuff, a displaced meniscus, a ruptured ACL, a nerve compressed by a herniated disc), cortisone addresses only the secondary inflammation, not the primary cause.
“This distinction is the most important thing I explain to patients before any injection. The question isn’t just ‘will this injection help?’ The question is ‘what’s causing your pain, and is cortisone the right treatment for that specific cause?’ A patient with rotator cuff impingement from a bone spur and secondary bursitis will often get significant relief from a subacromial injection. A patient with a full-thickness rotator cuff tear will get temporary relief from the same injection but the tear will still be there when it wears off, and it will likely be bigger. Those are completely different clinical situations that can look identical on the surface. In fact, a cortisone injection in someone with a tear that needs to be repaired, such as a rotator cuff tear, can hinder healing when the surgery is performed. They would therefore need to wait a few months before proceeding. A young patient with a tear that must be repaired to preserve the joint for many years to come, such as an ACL tear, should typically not receive a cortisone injection. Therefore, cortisone can be an excellent pain reliever but the doctor has to be certain the use is appropriate.” — Leon Popovitz, MD
Conditions Treated With Cortisone Injections at New York Bone & Joint
The following table covers the most common orthopedic indications for cortisone injections by body region, the specific injection target, and what the evidence supports in terms of expected outcomes.
| Body Region | Condition | Injection Target | What to Expect | Notes |
| Shoulder | Rotator cuff impingement & bursitis | Subacromial bursa | Good short-term relief (weeks to months). Allows physical therpay to proceed more effectively. [2] | Most effective when impingement is primary; not a substitute for evaluating for structural rotator cuff tear. [10] |
| Shoulder | Glenohumeral (shoulder joint) arthritis or synovitis | Glenohumeral joint space | Pain relief for inflammatory arthritis, post-traumatic synovitis. Duration varies by severity. | Not appropriate as primary treatment for labral tears, instability, or SLAP pathology. |
| Shoulder | Adhesive capsulitis (frozen shoulder) | Glenohumeral joint ± subacromial bursa | Reduces inflammation; can accelerate recovery when combined with physical therapy. Earlier injection may shorten course. | Best used alongside a structured stretching and physical therapy protocol. This has actually shown to be very effective if physical therapy alone is not making enough progress. |
| Shoulder | AC joint arthritis or osteolysis | AC joint | Targeted relief for isolated AC joint pain from arthritis or weight-lifter’s shoulder. | More precise than subacromial injection for isolated AC joint symptoms. |
| Knee | Knee osteoarthritis | Intra-articular (knee joint) | Consistent short-term pain relief. Duration typically 4–12 weeks. [3] | Frequency limits apply. Repeated injections in OA knees associated with accelerated cartilage loss. [4] [5] Evaluate for concurrent structural pathology. |
| Knee | Pes anserine bursitis | Pes anserine bursa (medial knee) | Typically good response. Often underdiagnosed cause of medial knee pain. | Distinguish from medial compartment OA or medial meniscus pathology: clinical examination is critical. |
| Knee | Patellar tendinitis / patellofemoral pain | Peritendinous / retropatellar | Limited evidence for direct tendon injection. Peritendinous injection may help. | Direct patellar tendon injection not recommended. Physical therapy and load management are primary treatment. |
| Hip | Greater trochanteric bursitis | Greater trochanteric bursa | Strong evidence for pain relief. First-line non-surgical treatment. [7] | Distinguish from gluteus medius/minimus tear; ultrasound guidance important to confirm bursal vs. tendon pathology. |
| Hip | Hip joint osteoarthritis | Intra-articular hip joint (image-guided) | Moderate evidence for short-term relief. Requires imaging guidance (ultrasound or fluoroscopy) for accurate placement. | Hip joint injection significantly harder to place accurately without guidance. Always image-guided at New York Bone & Joint. |
| Spine | Facet joint arthritis (cervical or lumbar) | Cervical or lumbar facet joints | Good relief when facet arthropathy is the primary pain generator. Duration variable. | Requires imaging guidance. Often performed by pain management specialists in conjunction with New York Bone & Joint evaluation. |
| Spine | Epidural (nerve root inflammation) | Epidural space | Indicated for radiculopathy from disc herniation with nerve root irritation. Reduces nerve inflammation. | Epidural injections performed by New York Bone & Joint pain management specialists. Not a substitute for structural evaluation when indicated. |
| Foot & Ankle | Plantar fasciitis | Plantar fascial insertion | Effective for refractory plantar fasciitis. Best after 6 weeks of failed conservative care. [9] | Ultrasound guidance recommended. Repeated injection risks plantar fascia rupture. |
| Foot & Ankle | Achilles tendinopathy | Peritendinous (NOT into tendon) | Peritendinous injection may reduce paratenon inflammation. Direct tendon injection contraindicated. | Never inject directly into the Achilles tendon due to risk of tendon weakening and rupture. New York Bone & Joint uses ultrasound guidance to confirm needle position. |
| Foot & Ankle | Ankle joint arthritis / synovitis | Ankle joint space | Useful for inflammatory arthritis and post-traumatic synovitis. | Ultrasound guidance improves accuracy in the ankle. |
| General | Inflammatory arthritis flare (rheumatoid, psoriatic, gout) | Affected joint | Cortisone is highly effective for acute inflammatory arthritis flares across any joint. | Coordinate with rheumatology for systemic management. Injection addresses local joint inflammation. |
Ultrasound-Guided Injections: The New York Bone & Joint Standard
Accuracy of needle placement is one of the most significant variables in injection outcomes. Studies show that ultrasound-guided injections achieve significantly better accuracy and clinical outcomes compared to landmark-guided (palpation-based) injections for most orthopedic targets. [8] At New York Bone & Joint, ultrasound guidance is the standard for injections where it improves accuracy, which includes hip joint injections, shoulder injections for deep or complex targets, greater trochanteric bursa injections, plantar fascia injections, and Achilles peritendinous injections.
What ultrasound guidance means in practice: your physician uses a real-time ultrasound image to visualize the target (such as the bursa, joint space, or soft tissue) and watch the needle advance to the exact location before injecting. There’s no guessing, no relying on surface landmarks, and no risk of inadvertent injection into adjacent structures. For structures like the hip joint, the Achilles tendon, and the plantar fascia where misdirection carries specific risks image guidance is not optional.
“Ultrasound also gives us diagnostic information at the time of injection. Before our doctors inject the subacromial space of a patient with shoulder pain, we scan the rotator cuff on ultrasound. If we see a significant full-thickness tear, then that changes the clinical picture. A tear may make an injection the wrong treatment or changes the injection target. The injection and the diagnostic ultrasound happen at the same visit. That’s a different level of care than a landmark injection based on where the patient reports pain.” — Leon Popovitz, MD
When Cortisone is the Wrong Treatment
This section is the most important thing on this page for a patient who has been offered a cortisone injection and is trying to decide whether it’s the right next step. Cortisone isn’t always the right answer. In some situations, it can actively delay the correct diagnosis or contribute to harm.
Conditions where cortisone isn’t the primary answer or carries specific risk:
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“The pattern I see most often is a patient who has received three or four cortisone injections over the past year or two, without any imaging more than an x-ray, with each one providing slightly less relief than the last. The diminishing response isn’t a coincidence. It’s the condition telling you that the inflammation is not the primary problem anymore, and that something structural is driving the pain. That’s the moment to stop injecting and start evaluating.” — Leon Popovitz, MD
| From Dr. Popovitz: When an Injection is the Right Answer, and When it Isn’t
A 52-year-old avid golfer came to see me with bilateral knee pain. He had been receiving cortisone injections (two per year in each knee) at another practice for about two years. Each injection provided relief, but the duration had shortened from about three months after the first injection to about six weeks after the most recent one. When I examined him and reviewed his imaging, the picture was more complex than bilateral osteoarthritis. The right knee had moderate medial compartment OA, and cortisone was a reasonable part of managing that. But the left knee had a posterior medial meniscus root tear that had been present on the MRI for at least a year and hadn’t been flagged. The root tear was what was causing the left knee pain. The cortisone was treating the resulting synovitis while the root tear caused arthritis to progress. We repaired the meniscus root tear on the left. For the right knee, we administered a properly spaced cortisone injection, started a targeted physical therapy protocol, and set a clear plan: if the right knee continued to deteriorate and became symptomatic despite optimal conservative care, we would discuss what was next. Now, he’s back to playing golf. The left knee feels significantly better than it has in two years. The right knee is managed, not ignored. The lesson isn’t that cortisone is bad. The lesson is that cortisone is a tool with specific indications. When the indication is right, it works. When it’s being used as a substitute for a diagnosis, it delays the right answer. My job is to know which situation I’m in before I pick up any instrument. — Leon Popovitz, MD |
What to Expect: Before, During, and After
Before the Injection
Your New York Bone & Joint physician will review your symptoms, examine the affected area, and confirm that cortisone injection is the appropriate next step for your specific condition. If you haven’t had recent imaging and the clinical picture warrants it, we may recommend an X-ray or MRI before proceeding. You don’t need to do anything special to prepare. You can eat normally, take your regular medications, and drive yourself to and from the appointment.
During the Injection
The procedure takes approximately 10–15 minutes from start to finish. The skin is cleaned and a local anesthetic may be applied. Using ultrasound guidance where indicated, the needle is advanced to the target location and the corticosteroid is injected. Most patients describe the procedure as mildly uncomfortable rather than painful. You’re awake throughout. No sedation is required. [1]
After the Injection
You may experience a temporary increase in pain or soreness at the injection site for 24–48 hours. This is a normal post-injection reaction called a steroid flare, and it resolves on its own. Ice and over-the-counter pain medication can help. Most patients experience meaningful pain relief within 3–5 days. We recommend avoiding strenuous activity for 24–48 hours post-injection, after which you can resume normal activities as tolerated.
Risks and Considerations
Cortisone injections are generally safe when administered appropriately and with adequate spacing. Risks to understand before proceeding: [1]
- Post-injection flare: Temporary worsening of pain for 24–48 hours after injection, caused by crystal-induced synovitis from the corticosteroid formulation. More common with certain formulations. Resolves without intervention.
- Skin and soft tissue changes: Repeated injections near the skin surface can cause localized depigmentation (skin lightening) or subcutaneous fat atrophy. More common with superficial injections and higher-concentration formulations. Minimized by appropriate injection depth.
- Blood sugar elevation: Cortisone can temporarily raise blood glucose, particularly in diabetic patients. If you have diabetes, monitor your blood sugar for 24–48 hours post-injection and inform your physician. If your diabetes is poorly controlled then it’s best not to do the injection and consult with your primary care doctor for better control before proceeding with the cortisone injection.
- Cartilage risk with repeated injections: Multiple studies have documented accelerated cartilage loss and osteoarthritis progression with frequent intra-articular corticosteroid injections in weight-bearing joints. [4] [5] This is why New York Bone & Joint limits injection frequency and re-evaluates patients whose relief duration is shortening.
- Tendon weakening: Repeated peritendinous injection near major tendons can weaken tendon tissue. Direct injection into the Achilles tendon body is contraindicated. Ultrasound guidance at New York Bone & Joint confirms needle position and prevents inadvertent tendon injection.
- Infection: Rare. Less than 1 in 10,000 injections in experienced hands with proper sterile technique. [1]
Why Choose New York Bone & Joint for Cortisone Injections?
| New York Bone & Joint Advantage | What It Means for You |
| Diagnosis first, injection second | Every patient receives a clinical evaluation before injection. We don’t administer cortisone as a reflex response to joint pain. The diagnosis determines whether injection is appropriate, and if so, exactly where. |
| Ultrasound guidance as standard | We use ultrasound guidance for injections where it improves accuracy: hip joint, shoulder, greater trochanteric bursa, plantar fascia, Achilles peritendinous. Not all practices do this. Accuracy matters. [8] |
| Honest expectations | We tell you how long relief is likely to last, how many injections are appropriate, and what a diminishing response means. We don’t schedule the next injection when the current one wears off. |
| Integrated care team | If your cortisone injection leads to a finding that warrants surgical evaluation, you’re already in the right practice. Our sports medicine physicians and orthopedic surgeons work together and communicate directly. |
| We know when to stop | When cortisone is no longer the right answer, we say so and tell you what comes next. We don’t continue injecting when the clinical picture has changed. |
| No hospital visit | All injections are performed at our Upper East Side and Midtown offices. In-office procedure, same-day appointment, no recovery time. |
| The bottom line
Cortisone is a valuable tool. Used correctly, it can be the difference between completing physical therapy and not, or between needing surgery now and not for years. Used incorrectly (as a substitute for diagnosis, on the wrong condition, or too frequently), it delays the right answer and sometimes causes harm. New York Bone & Joint’s approach is to know the difference before we act. |
References
- [1] American Academy of Orthopaedic Surgeons. Cortisone Shots. OrthoInfo. orthoinfo.aaos.org/en/treatment/cortisone-shot-steroid-injection
- [2] American Academy of Orthopaedic Surgeons. Shoulder Impingement/Rotator Cuff Tendinitis. OrthoInfo. orthoinfo.aaos.org/en/diseases–conditions/rotator-cuff-tears
- [3] American Academy of Orthopaedic Surgeons. Arthritis of the Knee. OrthoInfo. orthoinfo.aaos.org/en/diseases–conditions/arthritis-of-the-knee
- [4] Kompel AJ et al. Intra-articular corticosteroid injections in the hip and knee: perhaps not as safe as we thought? Radiology. 2019. pubmed.ncbi.nlm.nih.gov/31617798
- [5] McAlindon TE et al. Effect of intra-articular triamcinolone vs saline on knee cartilage volume and pain in patients with knee osteoarthritis: a randomized clinical trial. JAMA. 2017. pubmed.ncbi.nlm.nih.gov/28510679
- [6] Coombes BK et al. Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials. Lancet. 2013. pubmed.ncbi.nlm.nih.gov/20970844
- [7] American Academy of Orthopaedic Surgeons. Hip Bursitis. OrthoInfo. orthoinfo.aaos.org/en/diseases–conditions/hip-bursitis
- [8] Sibbitt WL et al. Does ultrasound guidance improve the outcomes of aspiration and injection of shoulder and knee joints? Scand J Rheumatol. 2012. pubmed.ncbi.nlm.nih.gov/22103390
- [9] American Academy of Orthopaedic Surgeons. Plantar Fasciitis. OrthoInfo. orthoinfo.aaos.org/en/diseases–conditions/plantar-fasciitis-and-bone-spurs
- [10] Goulart LT et al. Effectiveness of sub-acromial injections in rotator cuff injuries: A systematic review and meta-analysis. World J Orthop. 2025. pubmed.ncbi.nlm.nih.gov/40027967